IP Journal of Nutrition, Metabolism and Health Science
Official Publication of Khyati Education and Research Foundation
Official Publication of Khyati Education and Research Foundation
Print ISSN:-2582-6301
Online ISSN:-2582-628X
Review Article
Author Details :
Volume : 6, Issue : 4, Year : 2023
Article Page : 148-156
https://doi.org/10.18231/j.ijnmhs.2023.025
Abstract
An expanding understanding of the ability to alter meals or dietary to enhance health and lower the probability of nutrition-related conditions is what has sparked interest in nutrigenomics. It is a newly developed field which incorporates the areas of bioinformatics, diet, molecular biology, the study of genomes epidemiology, and molecular medicine to reveal the effects of diet on gene activity. More research in this area requires immediate attention to assist people recognize the connection between nutrition and well-being and to make sure all individuals receive advantages from the genomic change. As people's eating behaviors and daily routines change, they turn more vulnerable to diet-related disorders. The implementation of high quantities genomics technologies in studies on nutrition is known as nutrigenomics. If executed correctly, it will advance knowledge of how nutrition affects the processes of metabolism and homeostatic management, how this restriction is hampered in the initial stages of diet-related disorders, and the point to which specific sensitizing genotypes are responsible for such diseases. Nutrigenomics will eventually enable successful dietary approaches to restore homeostasis and eliminate diet-related illnesses. It is possible to think of nutritional genomics, also known as nutrigenomics, as the intersection of molecular nourishment and genome. The expression of genes profiles (transcriptome), chromatin design (epigenome), expression of proteins patterns, including posttranslational modifications (proteome), and metabolite profiles (metabolome) are only a few of the many tissue- and organ-specific effects of bioactive nutrients.The term "Nutrigenomics" was coined to signify the scientific investigation of this gene-nutrient interplay. Therefore, nutrigenomics refers to the application of the field of biochemistry physiology, dietary intake, genomics, proteomics, metabolomics, transcriptomics, and epigenomics to identify and understand the molecular basis of the current reciprocal relationships among genes and nutrients.Nutritional genomics, also known as nutrigenomics, is a research field of gene-nutrient relationships and how they are utilized. By changing the way genes are expressed and/or arrangement of someone's genetic code, ordinary food nutrients might alter the ratio across well-being and illness. This genetic insight can be obtained by nutritional genomics. The study of nutrigenetics looks at the associations between a person's gene makeup and particular nutritional intake. This subfield examines how genetic variability affects dietary guidelines or the relationship between diet and disease. Though they have different short-term goals, dietary research's long-term mission is to enhance people's health and aid in illness prevention. Gene-specific dietary data has provided a wealth of information that has helped doctors develop therapeutic strategies for the medical management of complex chronic diseases. The aforementioned data can be used in the future to a vast community; however, practicality needs to be verified. An understanding of nutrigenomics should soon enable more specialized therapies.
Keywords: Nutrigenomics, Nutrition, Transcriptomics, Proteomics, Metabolomics
How to cite : Salunkhe A A, Tamboli F A, Zade M S, Kore M D, Mhakle R A, Nutrigenomics: A new approach to the diagnosis and prevention of diseases. J Nutr Metab Health Sci 2023;6(4):148-156
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